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RT in PCNSL – Take home
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WBRT an effective tool in many stages of treatment
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Best use of RET is as low dose (24 Gy) after CR to MTX
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Full dose RT after MTX is toxic in age >60 years
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Chemotherapy alone in “full” MTX doses or with ASCT
transplant is also toxic, but is often considered
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Patients respond (yet, temporarily) to salvage with RT
alone or with chemotherapy