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Established CVD Risk factors

12%

¥

adjusted for mediastinal radiotherapy

Risk factor

RR

¥

95%CI

p

Diabetes mellitus

2.0

1.4-2.8

<0.001

Hypercholesterolemia

2.1

1.6-2.7

<0.001

Hypertension

1.5

1.2-2.0

0.001

Obesity (BMI≥30) at cut-off

1.6

1.2-2.2

<0.001

≥1 risk factors

2.5

1.8-3.4

<0.001

Recent smoker at cut-off (<5 yrs)

1.6

1.1-2.2

0.007

Van Nimwegen et al., submitted