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Conclusions CVD after HL

(literature and Dutch HL cohort)

After mediastinal RT increased riks of coronary events, valvular

disease, CHF

After 40 yrs: risk of any CVD after mediastinal

RT = 50% vs 26% (no mediastinal RT)

Risk remains increased ≥ 40 yrs

Younger age at RT

higher risk

Additive effects of RT and anthracyclines on CHF risk