Conclusions CVD after HL
(literature and Dutch HL cohort)
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After mediastinal RT increased riks of coronary events, valvular
disease, CHF
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After 40 yrs: risk of any CVD after mediastinal
RT = 50% vs 26% (no mediastinal RT)
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Risk remains increased ≥ 40 yrs
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Younger age at RT
higher risk
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Additive effects of RT and anthracyclines on CHF risk