Multivariable regression analysis
Cox model adjusted for sex and age. HR = Hazard ratio; 95% CI = 95% confidence interval
4.2 g/m
2
procarbazine≈3x MOPP or 6 MOPP-ABV(D)
CRC
Transverse colon
& rectum
Risk Factor
HR
95% CI
HR
95% CI
Treatment
Procarbazine
No CT or CT without procarbazine
1.0
Reference
1.0
Reference
CT, ≤ 4.2g/m
2
procarbazine
1.7
0.7-4.4
1.8
0.6-6.0
CT, > 4.2g/m
2
procarbazine
2.7
1.4-5.2
3.6
1.5-8.6
Radiotherapy
No infradiaphragmatic RT
1.0
Reference
1.0
Reference
Infradiaphragmatic RT
1.8
1.0-3.2
2.2
1.0-4.7