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“No Role” for Radiotherapy- The Primary Study

739 Patients III-IV HD

MOPP-ABV x 6-8 (2 cycles after CR)

57% CR 34% PR

333 (45%) CR randomized: 227 (31%) PR

24 Gy IFRT or no RT 30 Gy RT

EORTC H34

(Aleman et al.)

NEJM 248:24, 2003