423 / 1498
Randomized study of consolidation RT vs. Observation
in bulky (>5cm) HL patients who became
PET-negative
after chemotherapy
260 pts. with bulky (>5cm) HL
received chemotherapy (VEBEP)
30 non-responders. 70 CT-
negative and PET-negative
160 PET negative with CT>1.3cm
RANDOMIZED
80 pts. - Observation
80 pts.- IFRT (32 Gy)
Picardi M. et al. Leukemia & Lymphoma 2007