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Materials and Methods: Our
Approach
TheYale/MSK LymphomaGEP Collaboration
Create p tient database
for low grade lymphomas
Analyze patterns of local control
after RT, and select outlier cases
Perform (FFPE) gene expression profiling
Search for predictive gene signatures
Validate in the entire cohort
Extract RNA from archival (FFPE*) specimens
*FFPE=Formalin-fixed, paraffin-embedded tissue