Background Image
Table of Contents Table of Contents
Previous Page  945 / 1498 Next Page
Information
Show Menu
Previous Page 945 / 1498 Next Page
Page Background

Timing of peri-transplant RT

PRE- transplant

Pros:

Cytoreduction if poor salvage chemo

response

Less haematological toxicity

Ensures administration

Cons:

Higher risk of pneumonitis

Delay of HD chemo

Requires good co-ordination

POST- transplant

Pros:

Less pneumonitis

Less GI toxicity / VOD

No delay in giving HD chemo

Cons:

More haematological toxicity:

Irradiating regenerating marrow

MDS / leukemogenic risk

May be delayed or omitted if recovery is

prolonged