991 / 1498
Symptomatic (active) disease should be treated immediately, whereas
asymptomatic (smoldering) myeloma requires only clinical observation,
since early treatment with conventional chemotherapy has shown no
benefit
Investigational trials are currently evaluating the ability of
immunomodulatory drugs to delay the progression from smoldering
myeloma to symptomatic myeloma
The treatment strategy is mainly related to age
Treatment