2017_Imaging for Physicits

Dosimetry Literature

• +++ publications

• Absolute modeled TCP achieved by SIB ranged from 2-

15% and generally achieved with similar or small

increase to NTCP rectum

• Ability to dose escalate was anatomy dependent; lesions

within 5mm of rectal wall were difficult to dose escalate

• TCP/NTCP calculations highly dependent on accuracy of

GTV delineation

• Ability to boost independent of technique (fixed field

IMRT vs. VMAT; sequential vs. SIB) when considering

the effects of intra-fraction motion