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All reported results for ADC-based nodal staging
Lambrecht M. et al. Expert Rev Anticancer Ther 2010.
Study
Lesion size
(cm)
Mean ADC N+
(x 10
-3
mm
2
/sec)
Mean ADC N-
(x 10
-3
mm
2
/sec)
p-value Threshold
(x 10
-3
mm
2
/sec)
Sens
(%)
Spec
(%)
Wang et al.
Radiology 2001
> 1.0
1.13
±
0.43
1.56
±
0.51
0.002 1.22
84 91
Sumi et al.
J Neuroradiol 2003
> 1.0
0.41
±
0.11
0.30
±
0.06
< 0.01 0.4
52 97
Abdel Razek et al.
Eur Radiol 2006
0.9 – 1.5 1.09
±
0.11
1.64
±
0.16
< 0.04 1.38
98 88
Sumi et al.
AJR 2006
> 1.0
1.17
±
0.45
0.63
±
0.10
< 0.001 0.74
86 94
Vandecaveye et al.
Radiology 2009
0.4 – 1.5 0.85
±
0.27
1.19
±
0.22
< 0.0001 0.94
84 94
de Bondt et al.
Neuroradiology 2009
0.5 – 3.0 0.85
±
0.19
1.2
±
0.24
< 0.05 1.0
92 84
Holzapfel et al.
Eur J Radiol 2009
> 1.0
0.78
±
0.09
1.24
±
0.16
< 0.05 1.02
100 87
Perrone et al.
Eur J Radiol 2011
NA
0.85
1.45
< 0.01 1.03
100 93