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All reported results for DWI & response assessment
Dirix P. et al. Seminars in Radiation Oncology 2014.
Study
n During
CRT
After
CRT
Correlation Results
Kim et al.
Clin Cancer Res 2009
33 1w
2w
Response
after CRT
Baseline ADC of responders was significantly lower.
A significant increase in ADC was observed in responders
within 1 week of CRT which remained until after CRT.
Galban et al.
Transl Oncol 2009
15 3w
-
6-month LC Significant differences in ADC were observed between
patients with different outcomes.
Vandecaveye et al.
Eur Radiol 2010
30 2w & 4w -
2-year LRC The
Δ
ADC 2 and 4 weeks after the start of CRT was
significantly lower in lesions with recurrence.
King et al.
Eur Radiol 2010
50 2w
6w 2-year LRC A significant correlation was found between local failure and
post-treatment ADC but not pre- or intra-treatment ADC.
Hatakenaka et al.
IJROBP 2011
38 -
-
2-year LC
Baseline ADC of responders was significantly lower.
Vandecaveye et al.
IJROBP 2012
29 -
3w
2-year LRC The
∆ADC of lesions with later
recurrence was significantly
lower.
Srinivasan et al.
JCAT 2012
17 -
-
2-year outcome Baseline ADC of responders was significantly lower.
King et al.
Radiology 2013
30 2w
-
2-year LC
Baseline ADC showed no correlation with local failure.
During treatment, primary tumors showed a significantly
lower
∆ADC
for local failure.