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Inter-observer variations in delineation due to

limited soft-tissue contrast

Fiorino et al. 1998; Radiother. Oncol. 47:285-292

Leunens et al. 1993; Radiother.

Oncol. 29:169-175

UMC Utrecht data:

5 observers delineate

prostate on CT; standard

deviations of up to 4 mm