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Anaplastic Wilms’ Tumor

In NWTS-4, Stage I AH pts were treated with AMD

and VCR and had 2-yr overall survival estimates of

85.5% to 93.3% depending on AMD administration

regimen

Stage II to IV AH pts were treated with AMD, VCR

and DOX and had 4-yr overall survival rate of 27.1%

without CPM and 52.2% with CPM (p = 0.04)