IMPORT Study (UK)
•
Prospective clinical study (not RCT)
•
Aims to improve outcomes for WT and other childhood
renal tumours by testing the feasibility of a more
‘personalised’ approach to risk stratification
•
Identification and refine new biomarkers (molecular,
proteomic and imaging defined) for the management of
the whole spectrum of childhood renal tumours
•
Biological characterisation of tumour, blood and urine
samples
•
Central review of pathology and imaging
•
Treatment according to recently closed phase III SIOP
Renal Tumours Study Group
•
Will inform design of future SIOP clinical trial, which
will incorporate a more personalised assessment of
relapse risk versus first line therapy burden