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High risk neuroblastoma : Local RT

Indications

> One year

Infants if

MNA

Unresectable Localized at

diagnosis

Unfavorable histology

> 18months

MNA

No MNA

LINES prospective trial

Preop chemotherapy

Surgery

Post op chemotherapy

RT 21 GY

Metastatic at

diagnosis

HRNBL1.

5

MNA = MYCN amplification

RT for Neuroblastoma-

Anne LAPRIE-