1204 / 1708
Benefit of IMRT in UCNT : local control and survival
(Adults)
N
Time of RT5 y Local Control 5-y DFS 5-y OS Benefit
Peng, Radiother Oncol. 2012
CRT: 306 2003-2008 84.7% (T4 62%)
67.1%
IMRT : 310
90.5% (T4 81%)
79.6%
Chen, Oncotarget 2017
CRT: 377 2004-2006 76.6%
71.8%
Advanced disease
++
IMRT : 481
87.6%
82.3%
T4 ++
Zhang, Eur J Cancer 2015
CRT: 4836 2002-2012 90.8%
76.6% 84.5% Both advanced and
IMRT : 2245
95.6%
82.1% 87.4% early disease
- Randomized study in adults := better LC : + 6-11% DFS/OS : +5-12%
- Better target coverage using IMRT
- Advanced disease especialy : T4, N2, Stage III ++)