N
Time of RT 5 y Local Control 5-y DFS
5-y OS
Laskhar, Int J Radiat Oncol Biol Phys 2008 CRT: 17 2003-2006 68.2% (2-y)
IMRT : 19
84.2% (2-y)
Qiu, J Cancer Res Clin Oncol2017
CRT: 74 2003-2013 88.3%
71.2% 76.1%
IMRT : 102
97.9%
85.7% 90.4%
Liu, Radiat Oncol 2014
CRT: 103 1990-2011 No difference
No difference
IMRT : 55
- No randomized study in childhood
- The most recent large retrospective study confirms the benefit in term of :
- Local control : + 9%
- Survival +14%
Benefit of IMRT in UCNT : local control and survival
(children)