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Main studies in children
•
Huang
(ijrobp 2002) : dose to inner ear for medulloblastoma
decrease from 54 gy to 36,7 gy
but
boost not restricted to
tumor bed
•
Parker
( ijrobp 2007) : imrt for csi decrease the V10 gy but
increase integral dose
•
Wolden
(ijrobp 2005 ) :28 RMS treated with IMRT ; 1 local
relapse , no secondary tumor
•
Schroeder
(ijrobp 2015) :22 ependymomas .no marginal
failures .No grd >2 after 36 m FU
•
La
(ijrobp 2006) : 26 ewing sarcoma : no differences for LC
with 3 or 2 D but allow dose escalation without toxicites