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0.0004): 45% for infratentorial and 20% for supratentorial

tumor location.

Conclusion

The advent of conformal radiation therapy has provided a

renewed interest in radiation therapy for the frontline

management of ependymoma, especially for younger

patients. Selected contemporary series report high rates of

tumor control and overall survival (Table

3

) for favorable

patients now confirmed with longer-term data. These data

provide a basis for future studies that will attempt to

improve upon the results achieved with modern surgery and

radiation therapy using additional forms of adjuvant and

possibly systemic therapy.

Acknowledgments

This work was supported in part by American

Cancer Society and by the American Lebanese Syrian Associated

Charities (ALSAC).

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