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Table 1. Clinical and salvage treatment information for study patients (

Continued

)

Reirradiation

volume

Lesions/

surgery sites

Resection or

metastasectomy

results

Interval

RT1 RT2 (mo)

RT

age (Y)

CSI dose

(Gy)

RT2 irradiation sites

Maximal

reirradiation

dose (Gy) and site

RT2

failure

Patient

Site 1 (Gy)

Site 2 (Gy)

Site 3 (Gy)

25

CSI

1/1

NTR

29.9

6.6 39.6 4

th

ventricle (54.0)

— Cerebellum/stem

(113.4)

26

CSI

1/1

GTR

35.7

5.1 39.6 4

th

ventricle (54.0)

— Cerebellum/stem

(113.4)

27

CSI

1/1

GTR

4.2

5.4 39.6 L36 S1 (59.4)

— Cerebellum/stem (99.0)

28

CSI

4/3

STR

13.0

5.8 39.6 Lateral ventricles

(59.4)

Conus (54)

Sacrum (59.4) Cerebellum/stem (99.0) Metastases

29

CSI

1/1

GTR

22.3

4.7 39.6 Infundibular recess

(54.0)

— Cerebellum/stem (99.0)

30

CSI

3/1

GTR

20.5

4.0 39.6 Lateral ventricles

(59.4)

— Cerebellum/stem (99.0)

31

CSI

2/2

GTR

32.5

5.8 37.6 Frontal (55.8)

Finecal sac (57.6)

— Cerebellum/stem (93.6)

32

CSI

3/3

GTR

23.1

9.3 39.6 Foramen rotundum

(54.0)

L1 (54.0)

C7 (52.2)

Parietal (93.6)

33

CSI

1/1

GTR

23.6

4.2 41.4 Lateral ventricle (54.0)

— Cerebellum/stem (99.0)

34

CSI

1/1

GTR

24.3

4.8 39.6 Ca update (59.4)

— Cerebellum/stem (99.0)

35

CSI

5/3

GTR

25.3

13.3 39.6 T6 (54)

T12 (54.0)

— Cerebellum/stem (99.0)

36

CSI

1/1

GTR

28.0

3.7 39.6 Sylvian fissure (59.4)

— Cerebellum/stem (99.0) Metastases

37

CSI

2/2

GTR

43.7

10.2 39.6 Cervicomodullary

(57.6)

Conus (57.6)

— Parietal (93.6)

Metastases

38

CSI

1/1

STR

63.3

8.5 39.6 Fontal (59.4)

— Cerebellum/stem (99.0)

Abbreviations:

SRS = stereotactic radiosurgery; CSI = craniospinal irradiation; NTR = near-total resection; GTR = gross total resection; STR = subtotal resection; RT = radiation therapy; RT1=

initial radiotherapy; RT2 = reirradiation; CP = cerebellopontine.

Ependymoma reirradiation

d

T. E. M

ERCHANT

et al

.

91