Medulloblastoma
•
20% of paediatric brain tumours
•
Propensity for leptomeningeal
spread
•
Craniospinal Radiotherapy
(CSRT) essential
•
~ 30% have evidence of
leptomeningeal spread at
diagnosis
•
Radiosensitive (‘radio-curable’)
and chemosensitive
•
Long-term toxicity of treatments
problematic, particularly for
infants