Medulloblastoma histology
WHO 2016
•
There are long-established histological variants
of medulloblastoma that have clinical utility
(e.g., desmoplastic/nodular, medulloblastoma
with extensive nodularity, large cell, and
anaplastic)
•
It is now widely accepted that there are four
molecular genetic groups of medulloblastoma:
WNT-activated, SHH-activated, and the
numerically designated “group 3” and
“group 4”