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Medulloblastoma histology

WHO 2016

There are long-established histological variants

of medulloblastoma that have clinical utility

(e.g., desmoplastic/nodular, medulloblastoma

with extensive nodularity, large cell, and

anaplastic)

It is now widely accepted that there are four

molecular genetic groups of medulloblastoma:

WNT-activated, SHH-activated, and the

numerically designated “group 3” and

“group 4”