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Medulloblastoma - Randomised
Studies of Craniospinal RT Dose
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SIOP II (1984-1989)
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25 Gy - 55.3% 5 year EFS
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35 Gy - 67.6% 5 year EFS
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p = 0.07
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POG/CCG (1986 - 1990)
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23.4 Gy - 52% 8 year EFS
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36.0 Gy - 67% 8 year EFS
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p = 0.141