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Medulloblastoma
Differences between adults and children
•
Location: in children tends to arise in the vermis,
whereas in adults the cerebellar hemisperes are
primarily involved
•
Histopathological subtype: in children the
majority of histological subtypes consist of the
classical variant. In adults, the desmoplastic
variant is frequently found
•
Lesser frequency of metastatic disease: in
children generally 30%. In adult series the
incidence is 8-13%