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Dose Reduction in Low-Risk Rhabdomyosarcoma

Children’s Oncology Group D9602 Study

Eligibility:

1. nonmetastatic rhabdomyosarcoma in a favorable site

(orbit, non-parameningeal head and neck,

nonprostate/nonbladder genitourinary, biliary tract)

2. nonmetastatic rhabdomyosarcoma in an unfavorable

site with gross total resection of all tumor at diagnosis

(Group I or II)

3. initially alveolar subtype included (1997) but

later excluded (1999)

Breneman J et al. Int J Radiat Oncol Biol Phys 2012; 83:720-6