793 / 1708
Delayed Primary Excision and RT Dose
Modification
•
161 patients with Group III tumors (bladder dome, extremity,
trunk) enrolled on COG D9803 were evaluated
•
Seventy-three (45%) underwent DPE with removal of all gross
disease in 61 (84%)
•
43/73 had negative margins and received 36 Gy
•
19/73 had microscopic positive margins and received 41.4 Gy
•
The local 5-year local failure rate were 0% for bladder dome,
7% for extremity and 20% for trunk, similar to IRS-IV which
did not encourage DPE
Rodeberg DA et al. Int J Cancer 2015; 137:204-11