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Use MRI to identify extent of bony and soft tissue disease

GTV takes into account pre-chemo extent of disease

CTV 1.0-1.5cm margin, plus PTV margin

Except for large soft tissue mass extending into a body cavity

which responds to CTX and allows normal tissues to shift

back into position

Post-op RT

Not as well defined

Pre-op tumor bed with margins, c/d to any residual

Current RT Volume Recommendations

Appropriate modifications in tumors expanding into anatomical cavities

(thorax, pelvis) without infiltration