Practice Update | Onology

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Features
28
My Approach
Medullary
thyroid cancer
and its primary
treatment
30
Q & A
Critical issues in
thoracic oncology
Conference
10
American
Society
of Clinical
Oncology 2017
Annual Meeting
10 Practice changers in advanced
prostate cancer: STAMPEDE, LATITUDE
vis-à-vis CHAARTED
11 Practice changers in breast cancer
14 Ten practice changes I will make after
attending ASCO 2017
16 New standard of care for low risk
stage 3 colorectal cancer?
17 Extent of lymph node dissection in
prostatectomy: an update
18 Significant updates in glioblastoma
20 Novel treatment options for RCC: a
review
20 Practice changers in myeloma
Cover
6
Consensus
conference on
de-escalating
and escalating
treatments for
early-stage
breast cancer
RESEARCH
Editor’s picks
6 Consensus conference
on de-escalating and
escalating treatments for
early-stage breast cancer
7 Dabrafenib plus
trametinib in patients
with BRAF(V600)-
mutant melanoma brain
metastases (COMBI-MB)
8 Adjuvant pertuzumab
and trastuzumab in early
HER2+ breast cancer
9 Surgical resection vs
watchful waiting in low-
grade glioma
Breast
22 Risks of breast, ovarian,
and contralateral breast
cancer for BRCA1- and
BRCA2-mutation carriers
Melanoma
23 Adoptive transfer
of tumor-infiltrating
lymphocytes for metastatic
uveal melanoma
Colon & Rectum
24 Clinical implications of
monitoring circulating
tumor DNA in patients with
colorectal cancer
24 First-line chemotherapy
combined with cetuximab
or bevacizumab for KRAS
wild-type advanced or
metastatic colorectal
cancer
Genitourinary
26 Liquid biopsy analysis
of FGFR3 and PIK3CA
hotspot mutations for
disease surveillance in
bladder cancer
27 Similar oncological
outcomes with partial and
radical nephrectomy in
RCC ≥4 cm
PracticeUpdate Oncology is
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PracticeUpdate is guided by a world-renowned
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Editor-in-Chief Lee Schwartzberg MD FACP
Associate Editors Isabel Cunningham MD
Axel Grothey MD
Advisory Board Kimberly Blackwell MD,
Roxana Dronca MD, Wilfried Eberhardt MD,
Rafael Fonseca MD, Andre Goy MD,
Annette Hasenburg Prof Dr med, David Henry MD,
Eric Jonasch MD, Jeffrey Kirshner MD, FACP,
Ruben Niesvizky MD, Howard Scher MD,
David Straus MD, Roger Stupp MD
Editorial Contributors Brandt Esplin MD PhD,
Jeremy Jones MD, Jarushka Naidoo MD,
Moshe Ornstein MD, Erin Schenk MD PhD
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Cover: Dividing breast cancer cell.
CONTENTS 5
VOL. 1 • NO. 2 • 2017