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Conclusion

Finding the ‘best’ plan is a real challenge

Pareto navigation tools are very helpful in exploring the

solution area, however, navigation should be done in a

sensitive way

Keep track of the end result of each navigation to improve

the standard input

Treatment delivery time should be part of Pareto navigation

Lack of systematic differences between navigated and

deliverable plans makes it difficult to predict the dosimetric

change, its direction and its magnitude.