201
Biophysical Society 58
th
Annual Meeting, San Francisco, California
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3921-P
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B
oard
#B649
VINCULIN-MEDIATED CYTOSKELETAL REMODELING
MODULATES CARDIAC MORPHOLOGY AND CONTRACTILE
FUNCTION DURING AGEING.
Gaurav Kaushik
, Alice Spenlehauer,
Ayla Sessions, Danielle Pohl, Adriana Trujillo, Sanford I. Bernstein, Rolf
Bodmer, Anthony Cammarato, Adam J. Engler
3922-P
os
B
oard
#B650
NOVEL LOCATIONS; FAMILIAR FUNCTIONS: OBSCURIN AT
THE CARDIAC INTERCALATED DISC.
Maegen A. Ackermann
,
Nicole A. Perry, Aikaterini Kontrogianni-Konstantopoulos
3923-P
os
B
oard
#B651
ACETYLATION AND PHOSPHORYLATION POST-TRANSLA-
TIONAL MODIFICATIONS OF THE CAPZ BETA1 SUBUNIT
REGULATE FRAP DYNAMICS LEADING TO MYOCYTE HYPER-
TROPHY.
Ying-Hsi Lin
, Chad M. Warren, Brenda Russell
3924-P
os
B
oard
#B652
ACTIN CARBONYLATION IS HIGHER IN HUMAN HYPERTRO-
PHIC CARDIOMYOPATHY DUE TO MYH7 MUTATIONS.
Rosalie
Witjas-Paalberends
, Marcella Canton, Michelle Michels, Carolyn Ho,
Corrado Poggesi, Fabio di Lisa, Jolanda van der Velden
Microtubules, Their Motors, and
Associated Proteins II (Boards #B653–#B682)
3925-P
os
B
oard
#B653
STRUCTURAL KINETICS OF THE MITOTIC KINESIN EG5.
Joseph Muretta, William Behnke Parks, Karl Petersen, Adeline Goulet,
Carolyn Moores, David D. Thomas,
Steven Rosenfeld
3926-P
os
B
oard
#B654
STRUCTURAL BASIS FOR THE ASSEMBLY OF KINESIN-5 INTO
BIPOLAR ANTI-PARALLEL TETRAMERS. Jessica Scholey,
Stanley Nithianantham
, Jonathan M. Scholey, Jawdat Al-Bassam
3927-P
os
B
oard
#B655
KINESIN-5 MOTILITY IS REGULATED BY THE RESIDUE
CHEMISTRY OF LOOP-5.
Rebecca S. Buckley
, Victoria Dauphin,
Thomas M. Huckaba, Sunyoung Kim
3928-P
os
B
oard
#B656
A CHIMERIC KINESIN-5 MOTOR TRACKS PLUS-ENDS OF
MICROTUBULES.
Yalei Chen
, William O. Hancock
3929-P
os
B
oard
#B657
CUT7-DRIVEN MICROTUBULE SLIDING REVERSES DIRECTION
DEPENDING ON MOTOR DENSITY. Mishan Britto, Kanwal Zehra,
Adeline Goulet, Carolyn Moores,
Robert A. Cross
3930-P
os
B
oard
#B658
SRC PHOSPHORYLATION REGULATES THE HUMAN KINESIN-5,
EG5, AND DISRUPTS THE BINDING OF EG5 INHIBITORS.
Kathleen M. Gifford
, Joshua S. Waitzman, Taylor A. Poor,
Barbara Mann, Melissa C. Gonzalez, Pat Wadsworth, Sarah E. Rice
3931-P
os
B
oard
#B659
ALLOSTERIC L5-DIRECTED INHIBITORS OF KINESIN-5 CAN
CONTROL DIFFERENT BIOCHEMICAL INTERMEDIATES.
Minmin Luo
, Sunyoung Kim
3932-P
os
B
oard
#B660
PHOTO-REVERSIBLE INHIBITION OF MITOTIC KINESIN EG5
BY PHOTOCHROMIC STLC ANALOGUES COMPOSED OF
AZOBENZENE.
Kanako Tohyama
, Kumiko Ishikawa, Shinsaku Maruta
3933-P
os
B
oard
#B661
PHOTO-REGULATION OF KINESIN EG5 ATPASE AND MOTOR
ACTIVITY USING NOVEL PHOTOCHROMIC INHIBITOR
COMPOSED OF SPIROPYRAN AND CYSTEINE.
Kei Sadakane
,
Kumiko Ishikawa, Kanako Tohyama, Banri Yamanoha, Shinsaku Maruta
3934-P
os
B
oard
#B662
TRANSDUCER RESIDUES ARE THERMODYNAMICALLY
COUPLED IN THE KINESIN-5 MOTOR DOMAIN.
Jessica Richard
,
Hoang Nguyen, Elizabeth Kim, Sunyoung Kim
3935-P
os
B
oard
#B663
PHOTO-REGULATION OF MITOSIS KINESIN KIF18A USING
PHOTOCHROMIC INHIBITOR.
Seo Hideo
, Kumiko Ishikawa,
Shinsaku Maruta
3936-P
os
B
oard
#B664
PHOTOCONTROL OF MITOTIC KINESIN EG5 BY
INCORPORATING OF PHOTOCHROMIC MOLECULE INTO
THE FUNCTIONAL LOOP L5.
Kumiko Ishikawa
, Yuhki Tamura,
Shinsaku Maruta
3937-P
os
B
oard
#B665
THE KINESIN-1 GATING MECHANISM STUDIED BY
PRE-STEADY STATE KINETICS.
Erik Jonsson
, Ronald D. Vale
3938-P
os
B
oard
#B666
ENHANCED TRANSVERSE MOTION OF MULTIPLE
KINESIN MOTOR CONFIGURATIONS VIA A DIFFUSIVE
WEAKLY BOUND STATE.
David Ando
, Jing Xu, Ajay Gopinathan
3939-P
os
B
oard
#B667
KINESIN-2’S NECK-LINKER IS CRITICAL TO NAVIGATING
OBSTACLES ON THE MICROTUBULE SURFACE MORE
EFFICIENTLY THAN KINESIN-1.
Christopher L. Berger
,
Gregory J. Hoeprich, Andrew R. Thompson, William O. Hancock
3940-P
os
B
oard
#B668
STRAIN-BASED MECHANISM OF KINESIN ATPASE.
Wonmuk Hwang
, Matthew J. Lang, Martin Karplus
3941-P
os
B
oard
#B669
DEVELOPMENT OF MOLECULAR SHUTTLE REGULATED BY
EXTERNAL STIMULATION UTILIZING KINESIN ATP DRIVEN
MOTOR.
Naozumi Numata
, Kazunori Kondo, Shinsaku Maruta
3942-P
os
B
oard
#B670
COLLECTIVE MOTIONS AND DYNAMICAL COUPLINGS IN
THE KINESIN MOTOR DOMAIN.
Guido Scarabelli
, Barry J. Grant
3943-P
os
B
oard
#B671
INTRODUCING A KINESIN-INSPIRED NANOMOTOR
CONCEPT.
Martin J. Zuckermann
, Elizabeth H.C. Bromley,
Christopher N. Angstmann, Gerhard A. Blab, Nancy R. Forde,
Heiner Linke, Paul M.G. Curmi
3944-P
os
B
oard
#B672
SIMULATIONS OF NECK-LINKER MODIFIED AND ONE
HEAD LOADED KINESINS.
Norbert Orgován
, Imre Derényi
3945-P
os
B
oard
#B673
STRAIN-DEPENDENT REGULATION OF THE
KINESIN-1’S CATALYTIC ACTIVITY AS STUDIED BY
DISULFIDE-CROSSLINKING OF THE NECK LINKER.
Yamato Niitani
, Erik Jonsson, Ronald D. Vale, Michio Tomishige
3946-P
os
B
oard
#B674
KINESIN MOTILITY ON MICROTUBULE BUNDLES.
Leslie Conway
, Jennifer L. Ross
