200
Biophysical Society 58
th
Annual Meeting, San Francisco, California
3897-P
os
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oard
#B625
INVOLVEMENT OF TRPC IN THE SLOW FORCE RESPONSE
OBSERVED IN MOUSE VENTRICULAR MYOCYTES.
Yohei Yamaguchi
, Toshiyuki Kaneko, Keiji Naruse, Gentaro Iribe
3898-P
os
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oard
#B626
HYPERCHOLESTEROLEMIA PROTECTS AGAINST
ISCHEMIA-INDUCED VENTRICULAR TACHYCARDIA AND
VENTRICULAR FIBRILLATION.
Antonius Baartscheer
,
Cees A. Schumacher, Marieke W. Veldkamp, Arie O. Verkerk, Ruben Coronel
3899-P
os
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oard
#B627
APICO-BASAL GRADIENT OF REPOLARIZATION OVER THE
LEFT VENTRICLE DETERMINES ARRHYTHMIA
SUSCEPTIBILITY INMICE.
Morten B. Thomsen
, Tobias Speerschneider,
Søren Grubb, Søren-Peter Olesen, Kirstine Calloe
3900-P
os
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oard
#B628
EFFECT OF DIFFERENT CURRENTS AND EXTRACELLULAR
POTASSIUM ION CONCENTRATION ON ANODAL EXCITATION
OF CARDIAC TISSUE.
Sunil M. Kandel
, Bradley J. Roth
3901-P
os
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oard
#B629
EXAMINATION OF THE HEAT-STRESS RELATIONSHIP OF
RAT CARDIAC TRABECULAE USING AN IMPROVED MUSCLE
CALORIMETER.
Callum M. Johnston
, June-Chiew Han,
Bryan P. Ruddy, Poul M.F. Nielsen, Andrew J. Taberner
3902-P
os
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oard
#B630
SARCOMERE LENGTH NANOMETRY IN CARDIOMYOCYTES
EXPRESSEDWITH
α
-ACTININ-ACGFP IN Z-DISCS.
Seine A. Shintani
,
Kotaro Oyama, Takashi Ohki, Shin’ichi Ishiwata, Norio Fukuda
3903-P
os
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oard
#B631
DETERMINING THE MOLECULAR MECHANISMS THAT LINK
A TITIN MUTATION TO CARDIOMYOPATHY.
Brian Anderson
,
Julius Bogomolovas, Siegfried Labeit, Henk Granzier
3904-P
os
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oard
#B632
CARDIAC MYOFILAMENT SARCOMERE SHORTENING IS
FASTER AND EXHIBITS GREATER SHORTENING-INDUCED
COOPERATIVE DEACTIVATION AFTER PKA TREATMENT.
Laurin M. Hanft
, Kerry S. McDonald
3905-P
os
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oard
#B633
THE EFFECT OF
α
-ACTIN MUTANT E361G ON FORCE
GENERATION AND CROSS-BRIDGE KINETICS IN
THIN-FILAMENT RECONSTITUTED BOVINE CARDIAC
MUSCLE FIBERS. Fan Bai, Hannah M. Caster, John F. Dawson,
Masataka Kawai
3906-P
os
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oard
#B634
THE ACTC A295S MUTATION INCREASES HEART AND
SKELETAL MUSCLE CONTRACTILE ACTIVITY IN DROSOPHILA
MODELS OF HYPERTROPHIC CARDIOMYOPATHY.
Meera C. Viswanathan, Bernadette M. Glasheen, Kaylyn Bell,
Douglas M. Swank,
Anthony Cammarato
3907-P
os
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oard
#B635
DCM-CAUSING MUTATION E361G IN ACTIN UNCOUPLES
MYOFIBRIL CA
2+
SENSITIVITY FROM PROTEIN
PHOSPHORYLATION. Petr G. Vikhorev, Ross Wilkinson,
Weihua Song, O’Neal Copeland, Michael A. Ferenczi,
Steven B. Marston
3908-P
os
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oard
#B636
SARCOMERE NEUTRALIZATION THERAPY IN HCM/RCM:
THERAPEUTIC APPLICATION OF THE CALCIUMDESENSITIZER
W7 TO REMEDIATE HYPER-CALCIUM SENSITIVE DISEASE
STATES.
Brian R. Thompson
, Joshua Martindale, Joseph M. Metzger
3909-P
os
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oard
#B637
FUNCTIONAL ADAPTATIONS TO CARDIAC TROPONIN I
PHOSPHOMIMETIC SUBSTITUTIONS.
Sarah E. Lang
,
Margaret V. Westfall
3910-P
os
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oard
#B638
cpow
travel
awardee
MYOSIN HEAVY CHAIN ISOFORM SWITCHING IN SKELETAL
MUSCLES IN AN A8V-TROPONIN C HYPERTROPHIC
CARDIOMYOPATHY KNOCK-IN MOUSE MODEL.
Milica Vukmirovic
, Marcos A. Sanchez-Gonzalez, Edda Ruiz,
Eric Krivensky, David Dweck, Jose R. Pinto
3911-P
os
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oard
#B639
CARDIAC MYOSIN BINDING PROTEIN-C PHOSPHORYLATION
AND SARCOMERE FUNCTION.
Mohit Kumar
, Suresh Govindan,
Sakthivel Sadayappan, Pieter P de Tombe
3912-P
os
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oard
#B640
EFFECT OF A HIGH-SALT DIET ONTHE MECHANO-ENERGETICS
OF LEFT VENTRICULAR TRABECULAE ISOLATED FROM DAHL
SALT-SENSITIVE RATS.
Kenneth Tran
, June-Chiew Han,
Carolyn J. Barrett, Andrew J. Taberner, Denis S. Loiselle, Edmund J. Crampin
3913-P
os
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oard
#B641
OXYGEN CONSUMPTION OF BROWN ADIPOSE TISSUE
(BAT) AND SKELETAL MUSCLE IS INVERSELY RELATED.
Cecilie Sjåland, Jan Magnus Aronsen, Madelene Ericsson, Hong Qu,
Øyvind Ellingsen, Ivar Sjaastad, Geir Christensen, Kristin B. Andersson,
Per K. Lunde
, Ole M. Sejersted
3914-P
os
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oard
#B642
OPTOGENETIC G
S
ACTIVATION IN CARDIOMYOCYTES
ENHANCES PACEMAKER ACTIVITY.
Philipp Makowka
,
Tobias Bruegmann, Thomas Beiert, Philipp Sasse
3915-P
os
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oard
#B643
COMPARTMENTATION OF CAMP SIGNALING IN COMPLEX
AND SIMPLE CELLS.
Shailesh R. Agarwal
, Pei-Chi Yang,
Colleen Clancy, Robert Harvey
3916-P
os
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oard
#B644
UPREGULATION OF
α
1-ADRENERGIC INOTROPY IN FAILING
RIGHT VENTRICLE (RV) IS MEDIATED BY THE
α
1A
SUBTYPE.
Patrick M. Cowley
, Om Makwana, Audrey N. Chang,
Paul C. Simpson, James T. Stull, Anthony J. Baker
3917-P
os
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oard
#B645
CARDIAC-SPECIFIC OVEREXPRESSION OF FOXO AFFORDS
PROTECTION AGAINST AGE-ASSOCIATED DECLINE IN
CARDIAC PERFORMANCE IN THE DROSOPHILA MODEL.
Anna Blice-Baum
, Guarav Kaushik, Meera C. Viswanathan,
Rolf Bodmer, Adam J. Engler, Anthony Cammarato
3918-P
os
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oard
#B646
MYOSIN STORAGE MYOPATHY MUTATIONS DISRUPT
MYOFIBRILLAR ASSEMBLY/ STABILITY AND CAUSE
PROGRESSIVE MUSCLE DEGENERATION IN A DROSOPHILA
MODEL.
Meera Cozhimuttam Viswanathan
, William A. Kronert,
Girish C. Melkani, Anthony Cammarato, Sanford I. Bernstein
3919-P
os
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oard
#B647
EFFECTS OF FHC-RELATED TROPONIN T MUTATIONS
ON PROTEASOME ACTIVITY AND HALF-LIFE OF TROPONIN
T.
Jennifer E. Gilda
, Ziyou Cui, Aldrin V. Gomes
3920-P
os
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oard
#B648
MIRNA-448 IS A PRECURSOR OF ROS-DERIVED DYSTROPHIC
CARDIOMYOPATHY. Sergii Kyrychenko, Viktoriia Kyrychenko,
Yoshiyuki Ikeda, Junichi Sadoshima,
Natalia Shirokova
