190
Biophysical Society 58
th
Annual Meeting, San Francisco, California
3661-P
os
B
oard
#B389
PHOSPHORYLATION OF CARDIAC TROPONIN I AT TYROSINE
26 DECREASES THIN FILAMENT CALCIUM SENSITIVITY.
Hussam Salhi
3662-P
os
B
oard
#B390
EFFECT OF AMINO ACID CHANGES IN A TROPONIN I FHC
HOTSPOT ON PROTEIN:PROTEIN BINDING AND CALCIUM
SENSITIVITY OF FORCE DEVELOPMENT. Ziyou Cui,
Jennifer Gilda, Gaya Gomes,
Aldrin V. Gomes
3663-P
os
B
oard
#B391
IN VIVO ANALYSIS OF TROPONIN C KNOCK-IN (A8V)
MICE: EVIDENCE THAT TNNC1 IS A HYPERTROPHIC
CARDIOMYOPATHY SUSCEPTIBILITY GENE.
Adriano S. Martins
, Michelle S. Parvatiyar, Radjeep Turna,
Crystal Dawn Badger, Brittany Griffin, Diego Zorio, Milica Vukmirovic,
Marcos A. Sanchez-Gonzalez, David Dweck, Edda L. Ruiz,
Jingsheng Liang, Yincai Wang, J. M. Overton, Jose Renato Pinto
3664-P
os
B
oard
#B392
IN VITRO AND IN SITU STRUCTURE AND FUNCTION OF
THE CARDIAC TROPONIN C FAMILIAL HYPERTROPHIC
CARDIOMYOPATHY-LINKEDMUTATION, L29Q.
Ian M. Robertson
,
Ivanka Sevrieva, Monica X. Li, Malcolm Irving, Yin-Biao Sun,
Brian D. Sykes
3665-P
os
B
oard
#B393
TROPONIN I SER-150 PHOSPHORYLATION SUSTAINS
TROPONIN CA
2+
SENSITIVITY IN AN ACIDIC ENVIRONMENT.
Benjamin R. Nixon
, Shane D. Walton, Jonathan P. Davis,
Brandon J. Biesiadecki
3666-P
os
B
oard
#B394
DEFICIENCY OF SLOW SKELETAL MUSCLE TROPONIN T
CAUSES ATROPHY OF TYPE I SLOW FIBERS AND DECREASES
TOLERANCE TO FATIGUE.
Bin Wei
, Yingru Lu, J.P. Jin
3667-P
os
B
oard
#B395
ATTENTUATING THE DEPRESSIVE EFFECT OF ACIDOSIS
WITHMUTATIONS INTROPONIN ANDWITH 2-DEOXY-ATP.
Thomas J. Longyear
, Matthew A. Turner, Brandon J. Biesiadecki,
Joseph Lopez, Jonathan P. Davis, Edward P. Debold
3668-P
os
B
oard
#B396
THE EFFECT OF TRUNCATED TROPONIN COMPONENTS
ON ACTIVATION OF LETHOCERUS FLIGHT MUSCLE.
Belinda Bullard
, Bogos Agianian, Gian-Felice de Nicola,
Annalisa Pastore, Kevin Leonard
3669-P
os
B
oard
#B397
CHANGES IN THE ORIENTATION OF THE MYOSIN LIGHT
CHAIN DOMAIN (LCD) ASSOCIATED WITH THICK
FILAMENT-BASED REGULATION OF SKELETAL MUSCLE.
Luca Fusi
, Zhe Huang, Malcolm Irving
3670-P
os
B
oard
#B398
PHOSPHOLEMMAN-DEPENDENT REGULATION OF
NA/K-ATPASE MODULATES CONSTRICTION AND
RELAXATION IN AORTIC SMOOTH MUSCLE.
Andrii Boguslavskyi
, William Fuller, Michael J. Shattock
3671-P
os
B
oard
#B399
CARBONIC ANHYDRASE III CONTRIBUTES TO FATIGUE
TOLERANCE AND RECOVERY OF SKELETAL MUSCLE.
Han-Zhong Feng
, Jian-Ping Jin
3672-P
os
B
oard
#B400
PROTEIN-PROTEIN INTERACTIONS IN SKELETAL MUSCLE
CALCIUM TRANSPORT REGULATION.
Joseph M. Autry
,
Michael D. Schaid, Kurt C. Peterson, David D. Thomas
3673-P
os
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oard
#B401
FLUORESCENCE COMES OF AGE: MEASURING
ANGSTROM-LEVEL DISTANCE CHANGES WITHIN SINGLE
FILAMENTS OF REGULATED ACTIN.
John M. Robinson
,
Maria E. Moutsoglou, Christopher Solis Ocampo, Gi-Ho Kim
3674-P
os
B
oard
#B402
ROLE OF THE ESSENTIAL LIGHT CHAIN IN THE ACTIVATION
OF SMOOTH MUSCLE MYOSIN BY REGULATORY LIGHT
CHAIN PHOSPHORYLATION.
Kenneth A. Taylor
, Michael Feig,
Charles L. Brooks, III, Patricia M. Fagnant, Susan Lowey,
Kathleen M. Trybus
3675-P
os
B
oard
#B403
DEPENDENCE OF THE RATE OF PHOSPHATE DISSOCIATION
FROM ACTOMYOSIN-ADP-PI UPON THE ALKALI LIGHT
CHAINS IN SKELETAL MUSCLE MYOSIN.
David H. Heeley
,
Betty Belknap, Howard D. White
3676-P
os
B
oard
#B404
THE MECHANISM OF HCM-RELATED MUTATION R21C ON
THE MODULATION OF C-I INTERACTIONS AND CONTRACTILE
KINETICS.
Yuanhua Cheng
, Vijay S. Rao, Maria V. Razumova,
An-yue Tu, Luping Xie, Zhaoxiong (Charles) Luo, J. Andrew McCammon,
Andrew McCulloch, Michael Regnier
3677-P
os
B
oard
#B405
ACTIN-ACTIVATED ATPASE AND ACTIN SLIDING VELOCITIES
ARE SIMILARLY INFLUENCED BY ACTIN-MYOSIN BINDING
KINETICS.
Travis J. Stewart
, Samuel P. Dugan, Andrew Manfra,
Steven Bonzell, Christine R. Cremo, Josh E. Baker
3678-P
os
B
oard
#B406
EFFECTS OF EMD57033 AND EGCG ON MODULATION
OF CA
2+
-SENSITIVITY BY PKA PHOSPHORYLATION.
Andrew E. Messer
, Mary Papadaki, Steven B. Marston
3679-P
os
B
oard
#B407
OPTOGENETIC STIMULATION OF SKELETAL MUSCLES.
Tobias Brügmann
, Tobias van Bremen, Thorsten Send, Frank Holst,
Andreas Schröck, Philipp Sasse
3680-P
os
B
oard
#B408
TARGETING NRF2 ACTIVATION MODULATES X-ROS
SIGNALING IN DYSTROPHIC SKELETAL MUSCLE.
Christopher W. Ward
, Jaclyn P. Kerr, Ponvijay Kombairaju,
Thomas E. Sussan, Stephen J.P. Pratt, Richard M. Lovering,
Ramzi Khairallah, Shyam Biswal
3681-P
os
B
oard
#B409
MICROTUBULE NETWORK DENSITY TUNES
BOTH STRETCH AND CONTRACTION ACTIVATED X-ROS.
Jaclyn P. Kerr
, Benjamin L. Prosser, Guoli Shi, Natalia Becerra,
W. Jonathan Lederer, Roberto Raiteri, Christopher W. Ward
3682-P
os
B
oard
#B410
NIFEDIPINE TREATMENT IMPROVES MUSCLE FUNCTION
IN MDX MICE.
Francisco Altamirano
, Denisse Valladares,
Carlos Henriquez-Olguin, Mariana Casas, Jose R. Lopez, Paul D. Allen,
Enrique Jaimovich
