Do you believe pain or other symptoms originating from
non-bone need higher doses?
A.
Yes, because there is usually a larger mass that needs
higher dosage
B.
Yes, because because the cellular mechanisms are
different
C.
No, in principle, single doses should be as efficient as in
bone mets
D.
No, the philosophy is the same, for pain single doses, for
large masses higher doses
E.
No, it depends on life expectancy; < 3 months single
dose, > 3 months higher doses