1247 / 1578
/ 07.09.17
ESTRO SBRT 2017 - Matthias Guckenberger
35
0
1
2
3
4
5
6
7
prior RT End RT 1 week 2 weeks 3 weeks 4 weeks 5 weeks 6 weeks 3 months6 months9 months 12
months
VAS pain score
Time
DOSIS: a multi-center phase II trial
• Rapid, deep and durable pain reduction
/
Painful vertebral
metastases
Short life
expectancy
Longer life
expectancy
Conventional
radiotherapy
SBRT
radiotherapy
• ≤3mm GTV – SC
• Osteolytic
• >3mm GTV – SC
• Osteoblastic
Hypofractionated
SBRT
Single fraction
SRS
07.09.17
ESTRO SBRT 2017 - Matthias Guckenberger
36