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Contouring the Tumor

CT

CT + FDG-PET

Yamazaki H et al. Radiat Oncol. 2011 Jan 27;6:10.

Steenbakkers RJ et al. Radiother Oncol 2005, 77:182-90

Weltens C. et al. Radiother Oncol. 2001 Jul;60(1):49-59

Inter-observer variation, but do we know the truth?

CTV

GTV

Microscopic spread covered by dose-fall off