552 / 1578
Discussion: Clinical Relevance
▪
Should we measure intra-fraction motion?
▪
Yes, at planning in order to individualize the safety margin (and to
determine the time-averaged mean position)
▪
Should we correct for intra-fraction motion?
▪
Amplitude seems to have a minor effect on the margin. However,
▪
for central lesions and lesions close to the thoracic wall the
penumbra will be sharper
▪
Take care of small lesions and large amplitudes
▪
Should we correct for inter-fraction motion?
▪
YES!
▪
Dosimetrical effects?
▪
Be cautious for fast and single-fraction treatments