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A short history of intracranial SRS

1908:

Ø

Robert Henry Clarke and Victory Horsley:

Stereotactic

technique based on the reproducibility of the relationships

between landmarks on the skull (external auditory canals,

midline) and anatomical structures within the brain

1950s:

Ø

Lars Leksell:

Experiments with 250 kV rotating X-ray source (1951) and

stereotactic proton therapy (1955)

1967:

Ø

Lars Leksell:

Gamma-knife radiosurgery using

60

Co-sources for treatment of

functional disorders

1980s:

Ø

Oswaldo Betti and Frederico Colombo:

CT-localization and linac-based SRS

Betti

et al.

SBRT 2017 - D. Verellen

9