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Risks of complications

Core needle biopsies

Mortality 0.1% (fatal bleeding)

Complications

Bleeding/hematoma, pneumothorax, infection

Major (Requiring therapeutic intervention) 0.5%

Minor (No therapeutic intervention) 0.7%

(Mueller et al. BMC Gastroenterol 2012;12:173)

Risk depending on Quick-test and PTT, not platelet count

Consider risk of complications 1% → 2% with Calypso

(in a metaanalysis of liver biopsies from the UK, needle

size was not related to risk of complication (Howlett et al

Radiology 2013; 266(1): 226)