

Risks of complications
Core needle biopsies
•
Mortality 0.1% (fatal bleeding)
•
Complications
•
Bleeding/hematoma, pneumothorax, infection
•
Major (Requiring therapeutic intervention) 0.5%
•
Minor (No therapeutic intervention) 0.7%
(Mueller et al. BMC Gastroenterol 2012;12:173)
•
Risk depending on Quick-test and PTT, not platelet count
•
Consider risk of complications 1% → 2% with Calypso
(in a metaanalysis of liver biopsies from the UK, needle
size was not related to risk of complication (Howlett et al
Radiology 2013; 266(1): 226)