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S1001

ESTRO 36

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Results

IMRT and VMAT significantly improved the conformity to

the Planning Target Volume (PTV) and increased the

volume of PTV covered with 50Gy. This effect was clearly

illustrated in the region of the lateral field edges since it

is difficult to achieve in 3D-CRT due to the dose building

up effect. The lung volume received 20Gy in IMRT and

VMAT were higher than that of 3D-CRT but the result was

found to be not significant. The treatment time in terms

of number of monitor unit (MU) was found to be

significantly lower in 3D-CRT but the time required for

setting up the patient to the treatment position was

almost doubled to other two techniques.

Conclusion

IMRT and VMRT are well-accepted techniques and able to

provide encouraging dosimetric results for bilateral breast

irradiation. VMAT could further reduce the overall

treatment time because of the simple setup procedure

and the relatively small number of MU. This study

suggested that VMAT technique is feasible and is

recommended for bilateral breast irradiation.

EP-1828 Mean Dose in healthy lung for chest tumors

treated with Stereotactic Body Radiation Therapy

(SBRT)

J.l.Monroy Anton

1

, M. Asensio Martinez

2

, V. Borreda

Talon

2

, J. Hernandis Barbera

2

, M. Marco Collado

2

1

Hospital universitario de la ribera, radiation oncology,

alzira, spain

2

hospital universitario de la ribera, radiation protection

and radiophysics dpt, Alzira, Spain

Purpose or Objective

Stereotactic body radiotherapy (SBRT) is considered

treatment of choice in patients with pulmonary lesions not

candidates for surgical treatment.

High doses of radiation, both total and per fraction

,

requires a dose limitation in healthy organs at risk

(contralateral lung, heart, spine)

Our

objectives

were:

-- To evaluate the mean dose (Dm) received by the

contralateral lung in SBRT for thoracic lesions.

-- To analyze if PTV volume and/or total dose (TD) are

related to the Dm achieved

in the contralateral lung.

Material and Methods

A total of 26 pulmonary lesions treated with SBRT were

evaluated. Simulation was performed with CT 4D

respiratory gating and customized immobilization devices.

PTV was designed with an isotropic margin of 0.5 cm from

the GTV. Treatment was delivered with Linear Accelerator

( CLINAC, Varian), and verification done with internal

fiducial markers surrogates.

Results

Total Dose (TD) (Gy): range 20 – 45 Gy. Most cases (18;

69%) received a TD of

45Gy.

Dose/fraction: range 10-20 Gy/fr. The most frequent

fractionation was 15 Gy (20; 77%).

PTV volumen (cc): range between 10.18 - 99.33cc, with a

mean: 36.14cc ; median:

26.65cc

Healthy lung Dm (Gy): range 0.23 - 9.8 Gy; mean: 1.75Gy;

median: 1.25Gy

The increase in PTV volume did not associate an increase

in the average dose to the contralateral lung. Fig 1

An increase in total dose not involved an associated

increase in the dose to the healthy lung. Fig. 2

Conclusion

The Mean Dose received by the contralateral healthy lung

is

minimal.

No relationship was found between the increase in total

dose and increased in contralateral lung Dmean

No relationship was found between the volume of PTV and

Dmean reached in contralateral

lung

The parameters PTV and TD do not appear to relate to the

dose received to the contralateral

lung.

We can conclude that SBRT technique can be applied

safely largely preserving the healthy lung.

EP-1829 Dose delivery accuracy in total body

irradiation delivered with Step and Shoot IMRT

T. Berlon

1

, L. Specht

1

, P.M. Petersen

1

, L.S. Fog

1

1

Rigshospitalet, Clinic of Oncology- Department of

Radiotheraphy, Copenhagen, Denmark

Purpose or Objective

In total body irradiation (TBI) delivered with step and

shoot IMRT (SS IMRT), the dose conformity is considerably

improved compared with the more widely used TBI

delivered with open fields. This conformity is achieved

through the use of multiple fields defined by multileaf

collimators (MLCs). We aim to quantify the accuracy with

which TBI patients treated at our clinic were positioned,

and to determine the effect any positioning errors may

have had on the delivered dose.

Material and Methods

Images acquired as a routine part of the patient treatment

with the Theraview ™ (Theraview Technology, Leuden,

The Netherlands) imaging system were used to determine

the positioning shift in the cranio-caudal direction.

Images for 11 consecutive patients, each receiving 6

fractions, were analysed and the shifts recorded (figure

1). For 3 of the patients, only images for 5 of the 6

fractions were available.