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S1012

ESTRO 36

_______________________________________________________________________________________________

Results

Two hundred and four male patients were invited and

agreed to participate the study. The median age was 53.9

(30-74). Ninety four (46.1%) patients had buccal cancer,

46 nasopharyngeal cancer, 46 oro-hypopharyngeal cancer

and 12 laryngeal cancer. One hundred and thirty (63.7%)

patients had previous betal

quid chewing and 109

(53.4%)

had alcohol drinking. One hundred and three patients had

surgery, 191 chemotherapy and all had radiotherapy.

Thirty four (16.7%) patients had no religion belief and 30

(14.7%) had no job at interview. Sixty two (30.4%) patients

had continuing smoking, 18 (8.8%) patients continued

drinking and 6 (2.9%) betal quid chewing. Several

relationships had been found after analysis. The presence

of meaning had positive effect on global quality of life,

emotional well-being and total quality of life.

Furthermore, the low presence of meaning and high

search for meaning exhibited the lowest levels of general

quality of life, emotional well-being and total quality of

life. The presence of meaning has negative effect on

emotional distress. Furthermore the low presence of

meaning and high search for meaning exhibited the

highest levels of emotional distress. The longer duration

of smoking had less levels of presence of meaning and

search for meaning.

Conclusion

Individuals in the high presence of meaning showed a

better adaptation. Compared to those survivors having low

presence and low searching for meaning, the head and

neck cancer survivors having low presence of meaning and

high searching for meaning would have the most poorly

emotional

distress

and

quality

of

life.

EP-1851 Why is planned palliative radiotherapy often

cancelled? A retrospective exploratory study

H. Hansen

1

, M. Skovhus Thomsen

2

1

Aarhus University Hospital, Clinic for Radiotherapy and

Radiation Oncology, Aarhus C, Denmark

2

Aarhus University Hospital, Department of Medical

Physics, Aarhus C, Denmark

Purpose or Objective

In our department all appointments are booked when the

referral is received, i.e. a 100% pre-booking is performed.

In 2014-15 every 7th treatment course for patients

referred and booked to palliative treatment in our

department was cancelled before the planned start of

radiotherapy. This study investigated the reasons for

cancellations of palliative treatment courses prior to start

of radiotherapy as well as possible common denominators

among the cancelled patients

.

Material and Methods

A retrospective exploratory study of reasons for cancelling

planned palliative radiotherapy treatment was

established. Patients were included if they had been

booked for palliative radiotherapy treatment between

1January 2015 and 30 June 2015. Two sets of data were

collected. Firstly, data on age, gender and diagnosis was

collected on all planned palliative radiotherapy

treatments (n =787). Secondly, data on all patients who

had been cancelled before planned start of treatment

(n=105) was obtained. Data on cancelled patients included

demographic and clinical data as well as other relevant

data recorded in the time between referral to palliative

radiotherapy and cancellation. If a patient had been

cancelled more than once during the study period data

was only collected on the first cancellation.

Results

Of the 787 planned radiotherapy courses, 106 (13 %)

courses were cancelled before planned start of treatment.

Of the 106 courses cancelled, one patient accounted for

two cancelled treatments. The median time between

referral and planned start of treatment for the cancelled

courses was 14 days, showing that the majority of

cancelled patients were planned to start radiotherapy

much earlier than the maximum time limit of 28 days

specified

in

the

Danish

legislation.

Results of data collected on all planned palliative

radiotherapy treatments showed that patients' age,

gender and diagnosis did not differ between the courses

cancelled before planned start and courses started.

Main reasons for cancellation were death before start of

treatment, the patient being too weak to start treatment

or treatment was no longer relevant. Five of the 33

patients cancelled because they were too weak to receive

palliative radiotherapy, died in the time interval between

cancellation and the day they were supposed to start

treatment. The total number of patients who died before

planned start of treatment was 29 (28 %) (Table1).

Conclusion

The main reasons for cancelling palliative radiotherapy

were the patient either being too weak to receive

treatment/ dying before beginning of treatment or

because treatment was no longer relevant. The other data

collected could not explain the number of patients being

cancelled. More knowledge is needed about the

differences between patients starting palliative

radiotherapy treatment and patients being cancelled

before start of

treatment.

EP-1852 A research interventional clinic within the NHS

to enable participation in prostate clinical trials

K. Crowther

1

, A. O'Neill

1,2

, S. Murray

3

, J. Cousins

3

, O.

Stewart

3

, G. Totten

3

, S. Hynds

3

, K. Parsons

3

, P. Shiels

1

, C.

Logan

1

, D. Mitchell

1

, C. Lyons

1

, S. Jain

1,2

1

Cancer Centre- Belfast City Hospital, Radiotherapy,

Belfast, United Kingdom

2

Centre for Cancer Research and Cell Biology, Queen's

University, Belfast, United Kingdom

3

Belfast City Hospital, Northern Ireland Cancer Trials

Network, Belfast, United Kingdom

Purpose or Objective

Within prostate cancer clinical trials there has been an

increasing move towards hypo-fractionated and

Stereotactic Ablative Radiotherapy (SABR) regimes. This

has led to an increased requirement for Image-Guided

Radiotherapy (IGRT). At our centre, it was therefore

necessary to implement a service to facilitate the

implanting of fiducial markers (FM) and other

interventional procedures to enable our participation in

such clinical trials.

Material and Methods

Funding for this service was secured from a research

grant. A multi-disciplinary working group of Consultant

Clinical

Oncologists,

Radiographers,

Hospital

Management, Nurses, Clinical Trials team and Clinical

Research Fellows was formed. This group ensured the