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S562

ESTRO 36

_______________________________________________________________________________________________

Results

For the four patients, the DGART resulted to only one

replanning during the first week of treatment. For the

rectum wall V

72

, the overdose was on average reduced of

50% (100% maximum) and the mean dose reduced of 4.5

Gy compared to standard IGRT. For the bladder wall V

70

,

the overdose was on average reduced of 19% (37%

maximum) and the mean dose reduced of 6.6 Gy compared

to standard IGRT. For the prostate, the D

99

was on average

0.5 Gy higher (0.7 Gy maximum) using DGART compared

to standard IGRT.

Conclusion

DGART with only one replanning applied to a selected sub-

group of patients may reduce the rectum and bladder

overdose in prostate IGRT.

Poster: RTT track: Patient care, side effects and

communication

PO-1018 Improvement of radiation-induced late

toxicity after hyperbaric oxygen treatment

R. Roncero

1

, J. Pardo

1

, E. Jimenez-Jimenez

1

, D. Morera

2

,

N. Aymar

1

, I. Ortiz

1

, M. Vidal

1

1

Hospital Universitari Son Espases, Radiation Oncology,

palma de mallorca, Spain

2

Hospital Universitari Son Espases, Medical Physics,

palma de mallorca, Spain

Purpose or Objective

To assess the efficacy of hyperbaric oxygen therapy

(HBOT) in the management of patients with radiation-

induced late effects, in which more conservative

treatments have failed

Material and Methods

We retrospectively reviewed the clinical records of 33

patients treated at our Department, from 2012 to 2016,

who developed late toxicity (Grade IV CTCAE4.0) and

which did not respond to conservative treatment, and

recorded the variation, if occurred, in the degree of

toxicity after hyperbaric treatment. The average age of

the patients was 61 +/- 12 years and the mean dose

delivered during the radiotherapy treatment was 52 +/-

12Gy with standard fractionation. Regarding HBOT, they

received an average of 61 sessions. The patients presented

the following toxicities: enteritis/proctitis in 33%, bone

necrosis and sacroileitis in 30%, skin injury 9%, Cystitis 6%

and others 9% (neurocognitive impairment, dysphagia and

xerostomy).

In order to its evaluation, responses were classified into

three groups according the CTCAE4.0 scoring:

Major Response Group

: Improvement of toxicity from

Grade IV to Grade I or 0 (without toxicity, or minor toxicity

not requiring medical treatment),

Minor Response Group

: Improvement from Grade IV to

Grade III/II (permanent toxicity controlled with medical

treatment) and

No Response Group

. The statistical study was carried out

by using SPSS_22.

Results

Ninety-one percent of the patients (30) completed the

treatment sessions with hyperbaric chamber scheduled (2

patients didn´t start the treatment and 1 patient stopped

after 4 sessions). Statistical significant toxicity

improvement (p<0.05) was observed after the hyperbaric

oxygen treatment. 60% of the patients presented a Major

Response, and 18% presented a Minor Response. 9% (3) of

our patients were no responders. In our patients, no

relationship was founded between the response and the

age, the number of sessions of HBOT, or the time relapsed

since radiation treatment to the indication of the HBOT.

Table 1 presents the patients outcomes according the

toxicity.

Conclusion

In our patients, there is a significant improvement in late

radiation toxicity after HBOT, with the best responses

being observed in gastro-intestinal and bone toxicity.

PO-1019 Mobile Oncology: Survey with Healthcare

Professionals about Telemedicine, mHealth and mobile

Apps

K. Kessel

1,2

, M. Vogel

1

, F. Schmidt-Graf

3

, S. Combs

2,3

1

Technical University Munich TUM, Department of

Radiation Oncology, München, Germany

2

Institute for Innovative Radiotherapy iRT, Department

of Radiation Sciences DRS, Neuherberg, Germany

3

Technical University Munich TUM, Department of

Neurology, München, Germany

Purpose or Objective

Mobile applications (apps) are an evolving trend in the

medical field. To date, no native mobile applications for

smartphones or tablets in an oncological setting exist,

which support patients during therapy and follow-up and

allow for data analysis and/or direct feedback about

therapy parameters. Moreover, there is an ongoing

discussion whether such apps are really valuable, and

whether healthcare professionals (HCP) will accept their

use in clinical day-to-day life. Hence, we analyzed their

attitude about telemedicine, mHealth, and mobile apps.

Material and Methods

We developed an online survey with 24 questions

evaluating HCPs’ attitude towards telemedicine and

patients using medical mobile apps in general, as well as

specified questions on functionality and possible

disadvantages of an app. A link to the survey was sent to

all HCPs of our hospital via an in-house e-mail distributor

and lasted for six weeks.

Results

A total of 108 HCPs completed the survey. Of all, 88.9%

consider telemedicine as useful, 84.3% versus 15.7%

support the idea of an oncological app complementing

classical treatment. Automatic reminders, timetables,

laboratory results, and assessing side effects as well as

quality of life during therapy were rated as the most

important functions. In contrast, uncertainty regarding

medical responsibility (88.2%) and data security (82.3%)

were reasons mostly named by critics. The wish for

personal contact between HCP and patient (41.2%),

missing technical skills (23.5%) and disbelieving in

improvements of data documentation (23.5%) are

additional reasons. Of all respondents, 77.8% (84/108)

believe in a resulting time saving if collected data by an