Summary
Experience with IMRT and IGRT continues to grow.
IGRT:
provides explicit information to moderate uncertainties.
is currently limited to simple on-line interventions
must evolve to support more complex interventions
IGRT requires further development
Accumulate statistical models of organ movement and setup error.
Reduce time and effort required for re-planning
Planning and IGRT:
Adaptive control (driven by model-based feedback)
Robust control (driven by statistical models of uncertainty)
Incorporation of robust criteria reduces effort; e.g. replanning.
Formal methods for balancing trade-offs in control design




