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- high dose region is the most favorite place for the physicist
(and normally it is a very good choice!)
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find the best isocenter location with respect to:
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MLC limits
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use of wedges
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build up area, air cavities, bone
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isocenter position outside the high dose region often results in a
more complicated plan
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apply a-priori patient set-up translations if necessary
Where to place the isocenter?