Extreme breast hypofractionation –
preoperative external beam Radiotherapy
•
Phase I study:
1 x 15 Gy (n=8)
1 x 18 Gy (n=8)
1 x 21 Gy (n=16)
Followed by lumpectomy within 10 days
•
In low-risk patients
•
In prone position
•
Median follow-up: 23 months
•
Toxicity grade 1-2
•
Cosmetic outcome: good-excellent
Horton IJROBP 2015




