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Optic nerve tolerance & risk
Emami 1991 – (blindness within 5 years)
Probably too conservative
5% risk
50 Gy
50%
risk 65 Gy
Mayo 2010 – for 2.0 Gy/#
50 Gy
“
near zero
”
incidence
55 – 60 Gy
3 – 7%
risk
(Tolerance
might
be lower with co-morbidity)
Emami B et al IJROBP 1991; 21: 109-122
Mayo C et al IJROBP 2010; 76(3 Suppl): S28–S35 (QUANTEC)
96