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GTV N propositions

Lymph nodes which are proven malignant by biopsy or considered pathologic on

PET (focal accumulation above blood pool) are delineated as GTV. With respect to the

inter-observer variation of reporting FDG-positive mediastinal nodes, in doubt, a node

should rather be included

Lymph nodes that are FDG-PET-positive and EBUS/EUS-negative or negative in

mediastinoscopy should be included in the GTV as the false negative rates of EBUS/EUS

and mediastinoscopy are high

PET positive nodes may only be omitted, if there is clear non-malignant biopsy

explanation for the FDG positivity GTV Nor if a mediastinoscopy has been performed

showing no malingnancy in the nodes.