GTV N propositions
Lymph nodes which are proven malignant by biopsy or considered pathologic on
PET (focal accumulation above blood pool) are delineated as GTV. With respect to the
inter-observer variation of reporting FDG-positive mediastinal nodes, in doubt, a node
should rather be included
Lymph nodes that are FDG-PET-positive and EBUS/EUS-negative or negative in
mediastinoscopy should be included in the GTV as the false negative rates of EBUS/EUS
and mediastinoscopy are high
PET positive nodes may only be omitted, if there is clear non-malignant biopsy
explanation for the FDG positivity GTV Nor if a mediastinoscopy has been performed
showing no malingnancy in the nodes.