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CTV L2-L1: INDICATIONS

No or inadequate lymphadenectomy (L)

RT L4-L3-L2-L1

Bulky nodal disease

SN (+) (Macrometastases) without lymphadenectomy

AMAROS Trial (EORTC)

(Adjuvant Management of the Axilla Radiotherapy of

Surgery) is comparing L vs axillary RT with SN (+).

RT L4-L3-L2-L1

(Micrometastases: no RT)

AMAROS

Donker 2014 Lancet Oncol

Including 4800 patients demonstrated that axillary RT is as effective as axillary

surgery with less morbidity at 5 year follow-up.