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CTV IM: INDICATIONS

• Controversy:

• IN FAVOR: decreases LR

Freedman / Gustave-Roussy / Veronessi / Hos

t

AGAINST:

No decreases LR; fibrosis, cardiotoxicity

Fowble / Obedian

RT IM if SN (+) (histologically confirmed) in IM

Locally advanced disease, medial tumour with positive axillary

nodes

Trials: EORTC 22922 /

Canadian

NCIC MA20