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PTV

GTV

CTV

Adaptive radiation therapy

Yan et al.

Phys Med Biol

1997;42:123-32.

• Adaptive radiation therapy -

“a close-loop radiation treatment process where the treatment plan can be

modified using a systematic feedback of measurements.”

Measurements:

Anatomic: position, shape and volume

Dosimetric

Biologic: defined by multi-parameter biologic imaging